کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
743314 1462116 2012 8 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
One-step fabrication of poly(o-aminophenol)/multi-walled carbon nanotubes composite film modified electrode and its application for levofloxacin determination in pharmaceuticals
موضوعات مرتبط
مهندسی و علوم پایه شیمی شیمی آنالیزی یا شیمی تجزیه
پیش نمایش صفحه اول مقاله
One-step fabrication of poly(o-aminophenol)/multi-walled carbon nanotubes composite film modified electrode and its application for levofloxacin determination in pharmaceuticals
چکیده انگلیسی

In this study, one-step electrochemical polymerized method for the fabrication of poly(o-aminophenol)/multi-walled carbon nanotubes (PoAP/MWCNTs) composite film was developed for the quantitative determination of levofloxacin. Scanning electron microscopy and electrochemical methods were used to characterize the PoAP/MWCNTs nanocomposite film. The sensor fabricated from the nanocomposite film showed good stability and enhanced electrocatalytic ability for the detection of levofloxacin. The large current response of levofloxacin on PoAP/MWCNTs composite film-modified electrode could be ascribed to the synergistic effect of the electrocatalytic property of PoAP and MWCNTs. The oxidative peak current increased linearly with the concentration of levofloxacin in the range of 3.0–200 μM by differential pulse voltammetry, and the detection limit was 1.0 μM (S/N = 3). The proposed modified electrode also can be successfully applied to the determination of levofloxacin hydrochloride in pharmaceutical formulations.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Sensors and Actuators B: Chemical - Volume 174, November 2012, Pages 202–209
نویسندگان
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