Three-input chemical logic circuits based on a new fluorescent sensor for ATP and Cu2+in aqueous solution

A new l-lysine derivative featuring an anthracene unit is synthesized and characterized by elemental analysis, ESI-MS, 1H-NMR, and 13C-NMR. It can selectively bind ATP in acidic aqueous solutions, and be used as a highly selective fluorescent chemosensor for Cu2+ at neutral pH, resulting in fluorescence quenching. According to these characters, two combinational logic circuits are fabricated on a single molecule with three chemical inputs [H+(IN1), OH−(IN2), ATP (IN31)] and [H+(IN1), OH−(IN2), Cu2+(IN32)], respectively.