Surface hydrophilic treatment of polyurea film realized by vacuum ultraviolet light irradiation and its application for poly(methylmethacrylate) blood analysis chip

A room temperature hydrophilic method of the polyurea film surface was developed using vacuum ultraviolet (VUV) light at 172 nm in wavelength. The treated film has highly hydrophilic surface for long time (∼2 months). The stable hydrophilic surface, water contact angle of smaller than 20°, was realized. It is kept even after very hard condition of ultrasonic cleaning in de-ionized water. The polyurea film was applied for poly(methylmethacrylate) (PMMA) blood analysis chip. The performance of the surface treatment was evaluated by actual human whole blood flow. The new chip can reduce the adhesion of platelets and white blood cells, even after ultrasonic cleaning in surfactant-induced water.