کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
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746019 | 894439 | 2007 | 8 صفحه PDF | دانلود رایگان |
![عکس صفحه اول مقاله: Integrated microfluidic systems for automatic glucose sensing and insulin injection Integrated microfluidic systems for automatic glucose sensing and insulin injection](/preview/png/746019.png)
This paper presents a new microfluidic system capable of real-time measurement of glucose concentration and automatic insulin injection. The microfluidic system is composed of a microfluidic chip, a measurement and control circuit system, a compressed air source, and several electromagnetic valves to form a handheld system. The microfluidic chip is fabricated by using microfluidic techniques comprising of glucose sensing electrodes, a flow sensor and polydimethylsiloxane (PDMS)-based microfluidic structures such as micropumps, microvalves and microchannels. Commercially available needles are incorporated for continuous glucose monitoring and long-term insulin injection. The microfluidic system performs a variety of processes including blood sample collection, glucose concentration detection and injection of insulin. Compared with separate glucose monitoring and insulin injection platforms, the integrated system has a potential for on-line monitoring of glucose concentration and precise injection of proper doses of insulin. Even though this work is still in a preliminary stage towards practical applications, the developed microfluidic system has shown its potential to become a crucial tool for diabetes patients in the future.
Journal: Sensors and Actuators B: Chemical - Volume 122, Issue 2, 26 March 2007, Pages 461–468