کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
747408 | 894521 | 2006 | 5 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Protons and single nucleotide polymorphism detection: A simple use for the Ion Sensitive Field Effect Transistor
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کلمات کلیدی
موضوعات مرتبط
مهندسی و علوم پایه
شیمی
شیمی آنالیزی یا شیمی تجزیه
پیش نمایش صفحه اول مقاله
![عکس صفحه اول مقاله: Protons and single nucleotide polymorphism detection: A simple use for the Ion Sensitive Field Effect Transistor Protons and single nucleotide polymorphism detection: A simple use for the Ion Sensitive Field Effect Transistor](/preview/png/747408.png)
چکیده انگلیسی
The identification of single nucleotide polymorphisms (SNP) is a subject receiving considerable attention owing to the possibility of diagnosing and screening for diseases they are connected with. Currently, the emphasis for their detection is using DNA hybridisation methods and the development of novel, mainly fluorescent based methods for hybridisation detection. We report on a new method for identifying SNPs using Ion Sensitive Field Effect Transistor technology. Through the detection of single nucleotide mismatches, we show a procedure for effectively sequencing one base and therefore a mechanism for sequencing new DNA.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Sensors and Actuators B: Chemical - Volume 114, Issue 2, 26 April 2006, Pages 964–968
Journal: Sensors and Actuators B: Chemical - Volume 114, Issue 2, 26 April 2006, Pages 964–968
نویسندگان
Sunil Purushothaman, Chris Toumazou, Chung-Pei Ou,