The potential of ion mobility mass spectrometry for tuning synthetic host guest systems: A case study using novel zinc(II)dipicolylamine anion sensors

- Gas phase binding constants determined for macrocyclic anion sensors, with ligands.
- DTCCSHe measurements of macrocycles show structural tightening upon PPi binding.
- Structural changes occur during binding of non-optimised ligands.
- Computational models generated to support CCS results.