کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
7640447 | 1494853 | 2018 | 8 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Study on simultaneous determination of three nitroimidazole residues in honey by high performance liquid chromatography-resonance Rayleigh scattering spectra
ترجمه فارسی عنوان
مطالعه بر روی تعیین همزمان سه ترکیب نیترویمیدازول در عسل با طیفهای پراکندگی رلیزی کروماتوگرافی با رزکسیون با رزکسیون بالا
دانلود مقاله + سفارش ترجمه
دانلود مقاله ISI انگلیسی
رایگان برای ایرانیان
کلمات کلیدی
موضوعات مرتبط
مهندسی و علوم پایه
شیمی
شیمی آنالیزی یا شیمی تجزیه
چکیده انگلیسی
A novel and high sensitivity method that high performance liquid chromatography combined with resonance Rayleigh scattering is established for the determination of nitroimidazole residues in honey, including Metronidazole (MNZ), Ornidazole (ONZ) and Tinidazole imidazole (TNZ). In pHâ¯3.8 BR buffer solution, the three nitroimidazole drugs separated by HPLC, and then reacted with a post-column derivatization Phloxine B (PB) in the reaction tube to form 1:1 ion-association complex, which Leads to significant enhancement of the RRS signal. This paper optimized the experimental conditions of post-column derivation and discussed the mechanism of reaction for the enhancement of RRS signal. Under the optimal experimental conditions, the RRS signals of the three nitroimidazole drugs were enhanced with the increase of its concentration in the respective linear range. The detection limit (S/N) of MNZ, ONZ and TNZ was: 0.013â¯Î¼g·mLâ1, 0.049â¯Î¼g·mLâ1 and 0.27â¯Î¼g·mLâ1, respectively. The recovery rate was 97.4%-102.2%, and the relative standard deviation (RSD) does not exceed 5.3%, the reliability of this technique is verified, and the result of this method is satisfyingly.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Microchemical Journal - Volume 141, September 2018, Pages 423-430
Journal: Microchemical Journal - Volume 141, September 2018, Pages 423-430
نویسندگان
Fang Chen, ShiYu Li, Jingdong Peng, Xiang Wang, Huanjun Peng, Yu Chen, Yan He,