Antibacterial activity of DPEphos-containing ruthenium-nitrosyl complexes

The complex fac-[RuCl3(NO)(κ2-P,P′-DPEphos)] (1) was synthesized and characterized by 31P and 1H NMR, vibrational spectroscopy, ESI-MS, cyclic voltammetry. This complex was used to prepare the complexes with general formula trans-(NO,OMe)-[RuCl(OMe)(NO)(κ2-P,P′-DPEphos)(L)]PF6, (L = pyridine - py (2), 4-methylpyridine - 4-Mepy (3), 1-methylimidazole - 1-Meim (4) and 1H-benzimidazole - 1H-Benzim (5)). All complexes were assayed as antibacterial agents against the strains of bacteria E. coli (ATCC 25922), P. aeruginosa (ATCC 27853), S. aureus (ATCC 25932), S. epidermidis (ATCC 12228) and E. faecalis (ATCC 29212).159