Cerium-based metal-organic tetrahedron for selective sensing of ribonucleosides through the cooperation of hydrogen bonding interaction

By incorporating triamine-triazin as hydrogen bonding sites into the fragments of the ligands, Cerium-based metal-organic tetrahedron Ce-TBMN containing naphthalene fluorophore units has been used as an artificial chemosensor for selective recognition of guanosine over other ribonucleosides. Moreover, the size constraint of the tetrahedron benefited the selective fluorescent detection of GMP among the twelve ribonucleotides.