Dimeric ruthenium-triazolopyrimidine complex: Synthesis and structural characterization

Diruthenium(II) complex with the bridging 1,2,4-triazolo[1,5-a]pyrimidine (tp) ligand, of formulae [Ru2Cl2(μ2-Cl2)(dmso)2(μ-tp)]·H2O, was synthesized and characterized using various analytical tools (X-ray crystallography, IR and H, 13C, 15N NMR). Assays of in vitro cytotoxicity against two human cancer cell lines (A549 - non-small cell lung carcinoma and T47D - breast carcinoma) and normal mice fibroblasts (BALB/3T3) have been carried out.