Highly regio- and stereoselective hydrosilylation of β-fluoroalkylated α,β-unsaturated ketones

- Co2(CO)8-catalyzed hydrosilylation of β-fluoroalkylated α,β-unsaturated ketones gave the corresponding silyl enol ethers.
- Various fluoroalkylated silyl enol ethers could be synthesized under the very mild conditions.
- Thus-obtained silyl enol ethers could participate in the TiCl4-mediated stereoselective aldol reaction.
- Hydrosilylation and the following aldol reaction could be performed consecutively in an one-pot.