Short synthetic preparation of enantiomerically pure tetrafluoroethylenated sugar derivatives

► Short syntheses of tetrafluoroethylenated sugar derivatives could be realized. ► The syntheses involve the intermolecular reductive coupling of CH2CHCF2CF2Br and aldehydes. ► Four types of chiral sugar derivatives could be synthesized. ► Two types of chiral azasugar derivatives could be synthesized.