Geographical variation of isoquinoline alkaloids of Annona crassiflora Mart. from cerrado, Brazil

► Brazilian Cerrado is one of the 25 biodiversity hotspots for conservation priorities. ► Annonaceae presents high floristic richness in Cerrado areas. ► Isoquinoline alkaloids are an important characteristic of species of Annonaceae. ► Eight accessions of Annona crassiflora were analysed for alkaloid content. ► High quantitative and qualitative variations were observed among samples of A. crassiflora.