Design, synthesis, structure-activity relationships and X-ray structural studies of novel 1-oxopyrimido[4,5-c]quinoline-2-acetic acid derivatives as selective and potent inhibitors of human aldose reductase

Design, synthesis, structure-activity relationships and X-ray structural studies of novel 1-oxopyrimido[4,5-c]quinoline-2-acetic acid derivatives as selective and potent inhibitors of human aldose reductase

Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: European Journal of Medicinal Chemistry - Volume 152, 25 May 2018, Pages 160-174

Isidro Crespo, Joan Giménez-Dejoz, Sergio Porté, Alexandra Cousido-Siah, André Mitschler, Alberto Podjarny, Harris Pratsinis, Dimitris Kletsas, Xavier Parés, Francesc X. Ruiz, Kamel Metwally, Jaume Farrés,