کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
779933 1463488 2014 7 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Biodegradable non-aromatic adhesive polyurethanes based on disaccharides for medical applications
موضوعات مرتبط
مهندسی و علوم پایه سایر رشته های مهندسی مهندسی مکانیک
پیش نمایش صفحه اول مقاله
Biodegradable non-aromatic adhesive polyurethanes based on disaccharides for medical applications
چکیده انگلیسی

This work addresses synthesis, characterization, adhesive properties, protein adsorption and in vitro biodegradation of non-aromatic polyurethanes (NPUs). The following reactants were used in the syntheses of polyurethanes (PUs): non-aromatic 4,4'-Methylenebis(cyclohexyl isocyanate) (MCI), disaccharides (maltose and sucrose) and polyethylene glycol 200 (PEG 200). The NPUs exhibited low glass transition temperature (Tg) and good thermal stability. The dynamic contact angles on NPUs were influenced by the ratios of PEG 200-disaccharide monomer and the hard segment of the NPUs. The highest adhesion strength in whole polyurethanes was found as 307.6±50.1 kPa for 15% sucrose containing polyurethane. Protein adsorptions of polyurethane films were measured as average 10 µg Bovine Serum Albumin (BSA)/cm2 and 5 µg fibrinogen/cm2 for maltose, and 15 µg BSA/cm2 and 5 µg fibrinogen/cm2 for sucrose. Biodegradability ratios of NPUs were in the range of 15–35% for 8 weeks depending on the disaccharides containing NPUs.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: International Journal of Adhesion and Adhesives - Volume 49, March 2014, Pages 90–96
نویسندگان
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