Design, synthesis and in vitro and in vivo antitumour activity of 3-benzylideneindolin-2-one derivatives, a novel class of small-molecule inhibitors of the MDM2-p53 interaction

Design, synthesis and in vitro and in vivo antitumour activity of 3-benzylideneindolin-2-one derivatives, a novel class of small-molecule inhibitors of the MDM2-p53 interaction

Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: European Journal of Medicinal Chemistry - Volume 81, 23 June 2014, Pages 277-288

Guang-hui Zheng, Jia-jia Shen, Yue-chen Zhan, Hong Yi, Si-tu Xue, Zhen Wang, Xing-yue Ji, Zhuo-rong Li,