Antineoplastic activity of the thiazolo[5,4-b]quinoline derivative D3CLP in K-562 cells is mediated through effector caspases activation

► D3CLP was more cytotoxic to K-562 than PBMCs. ► D3CLP induced a subdiploid population without changes in the cell cycle phases. ► The TUNEL results are consistent with an apoptotic cell death induction. ► Effector caspases activity increase in function of the time.