Amberlite-IRA-402 (OH) ion exchange resin mediated synthesis of indolizines, pyrrolo [1,2-a] quinolines and isoquinolines: Antibacterial and antifungal evaluation of the products

► A number of indolizines and pyrrolo[1,2-a]quinolines/isoquinolines were prepared from phenacyl pyridinium, quinolinium and isoquinolinium salts reacting with alkynes and alkenes using amberlite-IRA-402 (OH) ion exchange resin as the base. ► Antibacterial and antifungal studies were carried out against thirteen bacterial and four fungal strains. ► Out of fifteen derivatives three (4a, 4b, 7a) are effective against all the thirteen strains. ► One derivative, 10, showed dual antibactericidal and antifungal efficacy.