Urea/thiourea derivatives of quinazolinone-lysine conjugates: Synthesis and structure-activity relationships of a new series of antimicrobials

► Quinazolinone-lysine conjugates and urea/thiourea/acetamide/sulphonamide derivatives. ► Several compounds exhibited highly potent antimicrobial activity. ► Urea/thiourea and F groups were found to be essential for potent results.