کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
7803162 | 1645397 | 2011 | 10 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Synthesis, glucose uptake activity and structure-activity relationships of some novel glitazones incorporated with glycine, aromatic and alicyclic amine moieties via two carbon acyl linker
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کلمات کلیدی
موضوعات مرتبط
مهندسی و علوم پایه
شیمی
شیمی آلی
پیش نمایش صفحه اول مقاله
![عکس صفحه اول مقاله: Synthesis, glucose uptake activity and structure-activity relationships of some novel glitazones incorporated with glycine, aromatic and alicyclic amine moieties via two carbon acyl linker Synthesis, glucose uptake activity and structure-activity relationships of some novel glitazones incorporated with glycine, aromatic and alicyclic amine moieties via two carbon acyl linker](/preview/png/7803162.png)
چکیده انگلیسی
⺠Three series of novel glitazones were designed, synthesized and analyzed. ⺠Compounds were synthesized both under conventional and microwave methods. ⺠Nineteen out of twenty four synthesized compounds were evaluated for their in vitro glucose uptake activity. ⺠Compounds, 6, 9a, 13a, 13b, 13c, 13f and 13h exhibited significant glucose uptake activity.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: European Journal of Medicinal Chemistry - Volume 46, Issue 3, March 2011, Pages 835-844
Journal: European Journal of Medicinal Chemistry - Volume 46, Issue 3, March 2011, Pages 835-844
نویسندگان
B.R. Prashantha Kumar, Mukesh Soni, S. Santhosh Kumar, Kuldeep Singh, Mohan Patil, R.B. Nasir Baig, Laxmi Adhikary,