Synthesis of a novel ester of hydroxytyrosol and α-lipoic acid exhibiting an antiproliferative effect on human colon cancer HT-29 cells

►A novel ester of hydroxytyrosol and α-lipoic acid is synthesized. ►It exhibits an antiproliferative activity on the human colon cancer HT-29 cells. ►The inhibition is mediated by the induction of a G2/M phase cell cycle arrest.