کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
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807765 | 1468288 | 2016 | 4 صفحه PDF | دانلود رایگان |
The detection of glucose by Surface Enhanced Raman Scattering (SERS) is a challenging problem because glucose molecules have a small Raman scattering cross-section and they have a low affinity for adsorption on metal nanoparticle surfaces. In this study we used 2-Thienylboronic acid (2-TBA) as a bridge or linker molecule between the metal surface and the glucose molecule and observed an intense Raman line at 986 cm− 1 that was used to quantify the glucose concentration in the molar concentration range 1 μM–500 μM. A good correlation was observed between the intensity of this line and molar concentration of glucose. These results would find applications in the development of a non-invasive glucose sensor for diabetic patients using saliva as the body fluid instead of blood serum.
Journal: Sensing and Bio-Sensing Research - Volume 9, July 2016, Pages 13–16