کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
826321 907918 2012 10 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Modeling the deposition of bioaerosols with variable size and shape in the human respiratory tract – A review
موضوعات مرتبط
مهندسی و علوم پایه شیمی شیمی (عمومی)
پیش نمایش صفحه اول مقاله
Modeling the deposition of bioaerosols with variable size and shape in the human respiratory tract – A review
چکیده انگلیسی

The behavior of bioaerosol particles with various size and shape in the human respiratory tract was simulated by using a probabilistic model of the lung and an almost realistic mathematical approach to particle deposition. Results obtained from the theoretical computations clearly show that biogenic particle deposition in different lung compartments does not only depend on physical particle properties, but also on breathing mode (nose or mouth breathing) and inhalative flow rate (=tidal volume × breathing frequency/30). Whilst ultrafine (<100 nm) and large (>5 μm) particles tend to accumulate in the extrathoracic region and the uppermost airways of the tracheobronchial tree, particles with intermediate size are characterized by higher penetration depth, leading to their possible accumulation in the lung alveoli. Due to their deposition in deep lung regions and insufficient clearance, some bioaerosol particles may induce severe lung diseases ranging from infections, allergies, and toxic reactions to cancer.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Journal of Advanced Research - Volume 3, Issue 4, October 2012, Pages 295–304
نویسندگان
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