Baseline, one and three month changes in the peripapillary retinal nerve fiber layer in acute optic neuritis: Relation to baseline vision and MRI

RNFL swelling, most likely due to axoplasmic stasis from blockade at the lesion site in optic neuritis, is seen with OCT better than SLP. RNFL swelling in some quadrants and loss in others occur at 1 month and is well seen with interocular comparison by both methods. Optical imaging provides pathophysiologic as well as quantitative information regarding axonal changes.