کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
8283401 1535185 2009 4 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
FHM3 in familial hemiplegic migraine is more resistant to mutation than FHM1 and FHM2
موضوعات مرتبط
علوم زیستی و بیوفناوری بیوشیمی، ژنتیک و زیست شناسی مولکولی سالمندی
پیش نمایش صفحه اول مقاله
FHM3 in familial hemiplegic migraine is more resistant to mutation than FHM1 and FHM2
چکیده انگلیسی
Familial hemiplegic migraine (FHM) is a rare subtype of migraine with aura and transient hemiplegia. CACNA1A (FHM1) gene, the ATP1A2 (FHM2) and the SCN1A (FHM3) are reported for their correlation to FHM. Here, a bioinformatics analysis was done to study the risk positions for mutation within the amino acid sequence of the three mentioned molecules. In this work, the author can identify many mutant prone positions within the studied FHM. Of interest, the author detected that FHM3 is a high resistant molecule when compared to FHM1 and FHM2.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Journal of the Neurological Sciences - Volume 277, Issues 1–2, 15 February 2009, Pages 76-79
نویسندگان
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