Pituitary adenylate cyclase-activating polypeptide (PACAP) stimulates release of somatolactin (SL)-α and SL-β from cultured goldfish pituitary cells via the PAC1 receptor-signaling pathway, and affects the expression of SL-α and SL-β mRNAs

► PACAP stimulates the release of SL-α and SL-β from cultured goldfish pituitary cells. ► PACAP also enhances the expression of SL-β mRNA, but not SL-α mRNA. ► The action of PACAP is blocked by PACAP(6-38).