Therapeutic benefits of 9-amino acid peptide derived from prothymosin alpha against ischemic damages

The purpose of study is to determine the minimum peptide sequence in prothymosin alpha that provides neuroprotection against ischemic stress. The major finding is that 9-amino acid peptide sequence P9 (a.a. 52-60) in ProTα rescues ischemia-induced cellular and functional damages in vitro and in vivo. Detailed about P9-induced neuroprotection may confer a therapeutic benefit for the treatment of ischemic damages.