Gonadotropin-releasing hormone neuropeptides and receptor in human breast cancer: Correlation to poor prognosis parameters

► GnRH I and II and their receptor were examined in breast cancer biopsies. ► Quantification was performed by a multiplex real-time RT-PCR assay. ► All genes were twice as frequently detected in tumor than adjunct benign tissue. ► Expression of each gene was correlated to the others and poor prognosis parameters.