Increased plasma levels of intermedin and brain natriuretic peptide associated with severity of coronary stenosis in acute coronary syndrome

► Plasma IMD and BNP levels were markedly higher in ACS patients than that in controls. ► The increased plasma IMD and BNP levels were positively correlated with degree of coronary stenosis in ACS patients ► Plasma levels of IMD were positively correlated with BNP levels in all subjects.