کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
8396458 1544152 2014 6 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Fungal ribotoxins: Natural protein-based weapons against insects
ترجمه فارسی عنوان
ریبوتوکسین قارچی: سلاح های طبیعی مبتنی بر پروتئین در برابر حشرات
موضوعات مرتبط
علوم زیستی و بیوفناوری بیوشیمی، ژنتیک و زیست شناسی مولکولی بیوشیمی، ژنتیک و زیست شناسی مولکولی (عمومی)
چکیده انگلیسی
Ribotoxins are fungal extracellular ribonucleases highly toxic due to their ability to enter host cells and their effective ribonucleolytic activity against the ribosome. The natural role of these proteins in the producing fungi is still unsolved. Nevertheless, recent studies showing the insecticidal properties of two ribotoxins from different origin support their involvement in defense mechanisms. Thus, it seems that not just the entomopathogen Hirsutella thompsonii expresses the ribotoxin hirsutellin A as a virulence factor but also Aspergillus, the main ribotoxin producer, does so. In this review we focus on this little known aspect of this family of proteins, their toxicity against insects, from the point of view of its biological relevance and its potential biotechnological applications.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Toxicon - Volume 83, 1 June 2014, Pages 69-74
نویسندگان
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