Continuous IV Crotalidae Polyvalent Immune Fab (Ovine) (FabAV) for selected North American Rattlesnake bite patients

► Some rattlesnake envenomated patients develop severe late hematologic venom effects. ► We managed five patients with a novel treatment of continuous IV Fab antivenom. ► All patients responded to 3-4 vials of antivenom per 24 h for 6-14 days. ► The safety and efficacy of this treatment approach requires additional study.