Multiple organ dysfunction: A delayed envenomation syndrome caused by tentacle extract from the jellyfish Cyanea capillata

► We established a delayed jellyfish envenomation syndrome (DJES) model. ► Effects of jellyfish venom on the vital target organs were monitored. ► Multiple organ dysfunction was induced by tentacle extract from Cyanea capillata. ► Liver and kidney injuries might be the leading causes of death in rats with DJES.