Effect of Australian elapid venoms on blood coagulation: Australian Snakebite Project (ASP-17)

► A mathematical model of the coagulation network has been developed. ► The model predicted observed clotting factor vs time data for Australian snake bites. ► Complete VICC may result in higher depletion of clotting factors than partial VICC. ► “Xa:Va-like” venoms may produce more severe VICC than “Xa-like” venoms.