Generation and characterization of human induced pluripotent stem cell lines from a familial Alzheimer's disease PSEN1 A246E patient and a non-demented family member bearing wild-type PSEN1

Resource table.Unique stem cell lines identifierUOWi002-AUOWi003-AAlternative names of stem cell linesiPSC 6846.2 (UOWi002-A)iPSC 6848.2 (UOWi003-A)InstitutionIllawarra Health and Medical Research Institute, University of WollongongContact information of distributorLezanne Ooi, lezanne@uow.edu.auType of cell linesiPSCOriginHumanCell sourceDermal fibroblastClonalSingle cloneMethod of reprogrammingTransgene freeMultiline rationaleFamily members, one demented patient with a familial Alzheimer's disease mutation and one non-demented controlGene modificationNoType of modificationN/AAssociated diseaseNon-demented control (UOWi002-A)Familial Alzheimer's disease (UOWi003-A)Gene/locusN/A (UOWi002-A)PSEN1 A246E (UOWi003-A)Method of modificationN/AName of transgene or resistanceN/AInducible/constitutive systemN/ADate archived/stock date24/04/2018Cell line repository/bankN/AEthical approvalHE13/299 University of Wollongong Human Research Ethics Committee