کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
8455618 1548298 2018 6 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Mitochondrial mutations associated with hearing and balance disorders
ترجمه فارسی عنوان
جهش های میتوکندری مرتبط با اختلالات شنوایی و تعادل
موضوعات مرتبط
علوم زیستی و بیوفناوری بیوشیمی، ژنتیک و زیست شناسی مولکولی تحقیقات سرطان
چکیده انگلیسی
Hearing and balance disorders are related to the inner ear and are among the major cause of falls in older adults. Hearing loss that commonly occurs with aging (aka presbyacusis) can result from noise exposure, smoking, ototoxic drugs and genetic factors such as mutations in nuclear and mitochondrial genes. Mutations in mitochondrial DNA (mtDNA) have been reported to play an important role in cell function by providing energy, as well as, cell death (apoptosis). This study aims to systematically review mitochondrial mutations associated with presbyacusis and suggests preventive measurements to improve the quality of life in older adults.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis - Volume 810, July 2018, Pages 39-44
نویسندگان
, , , , ,