Formaldehyde-induced histone H3 phosphorylation via JNK and the expression of proto-oncogenes

- Formaldehyde modified histones.
- The phosphorylation of H3S10 was increased at the promoter regions of proto-oncogenes.
- The phosphorylation of H2AXS139 was attributed to FA-induced DNA damage.
- The FA-induced initiation and promotion of cancer could be judged by these modifications.