Hyperthermia-induced micronucleus formation in a human keratinocyte cell line

► Effects caused by various temperatures were investigated in HaCaT cells in vitro. ► Micronucleus frequencies were increased for all temperatures (38-42 °C). ► Apoptosis occurred at temperatures ≥39 °C. ► Proliferation was decreased at 41 °C and 42 °C. ► Hsp70 expression was elevated for all temperatures.