کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
8455987 | 1548363 | 2011 | 13 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Track structures, DNA targets and radiation effects in the biophysical Monte Carlo simulation code PARTRAC
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کلمات کلیدی
موضوعات مرتبط
علوم زیستی و بیوفناوری
بیوشیمی، ژنتیک و زیست شناسی مولکولی
تحقیقات سرطان
پیش نمایش صفحه اول مقاله
![عکس صفحه اول مقاله: Track structures, DNA targets and radiation effects in the biophysical Monte Carlo simulation code PARTRAC Track structures, DNA targets and radiation effects in the biophysical Monte Carlo simulation code PARTRAC](/preview/png/8455987.png)
چکیده انگلیسی
This review describes the PARTRAC suite of comprehensive Monte Carlo simulation tools for calculations of track structures of a variety of ionizing radiation qualities and their biological effects. A multi-scale target model characterizes essential structures of the whole genomic DNA within human fibroblasts and lymphocytes in atomic resolution. Calculation methods and essential results are recapitulated regarding the physical, physico-chemical and chemical stage of track structure development of radiation damage induction. Recent model extension towards DNA repair processes extends the time dimension by about 12 orders of magnitude and paves the way for superior predictions of radiation risks.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis - Volume 711, Issues 1â2, 3 June 2011, Pages 28-40
Journal: Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis - Volume 711, Issues 1â2, 3 June 2011, Pages 28-40
نویسندگان
Werner Friedland, Michael Dingfelder, Pavel Kundrát, Peter Jacob,