کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
8457259 1548802 2018 4 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Fatal serotonin syndrome in a patient with Marchiafava-Bignami disease: Combined neurological and psychiatric emergency
ترجمه فارسی عنوان
سندرم سرتوتین مرگبار در بیمار مبتلا به بیماری مارکیافوا-بیژنمی: اضطراب عصبی مرکب و روانپزشکی
کلمات کلیدی
سندروم سروتونین، بیماری مارکیاافوا-بیگینمی، سیتالوپرام،
موضوعات مرتبط
علوم زیستی و بیوفناوری بیوشیمی، ژنتیک و زیست شناسی مولکولی تحقیقات سرطان
چکیده انگلیسی
Marchiafava-Bignami disease (MBD) is a rare fatal neurological disorder characterized by demyelination, primary degeneration, and necrosis of the corpus callosum. Although MBD is mostly associated with chronic alcohol consumption and malnutrition, it has been reported in non-alcoholic patients. Serotonin syndrome is a rare but potentially fatal side effect of antidepressants that results from overstimulation of both central and peripheral serotonergic receptors. In this report, we present a case with fatal serotonin syndrome happening in a non-alcoholic patient with the chronic form of MBD. To our knowledge, this case is the first report of fatal serotonin syndrome due to citalopram in an MBD patient. The present report may indicate that citalopram and other SSRIs should not be used in patients with MBD. Our case is also among few reported cases in the literature where no cause was identified in a patient with no previous history of alcohol intake.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Neurologia i Neurochirurgia Polska - Volume 52, Issue 2, March 2018, Pages 277-280
نویسندگان
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