کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
8506867 | 1555936 | 2017 | 8 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Significant decline in lymphatic filariasis associated with nationwide scale-up of insecticide-treated nets in Zambia
ترجمه فارسی عنوان
کاهش قابل توجهی در فلیاریوز لنفاوی همراه با گسترش شبکه های تحت پوشش حشره کش در سراسر کشور در زامبیا
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کلمات کلیدی
موضوعات مرتبط
علوم زیستی و بیوفناوری
علوم کشاورزی و بیولوژیک
علوم کشاورزی و بیولوژیک (عمومی)
چکیده انگلیسی
Lymphatic filariasis (LF) is a mosquito-borne disease, broadly endemic in Zambia, and is targeted for elimination by mass drug administration (MDA) of albendazole and diethylcarbamazine citrate (DEC) to at-risk populations. Anopheline mosquitoes are primary vectors of LF in Africa, and it is possible that the significant scale-up of malaria vector control over the past decade may have also impacted LF transmission, and contributed to a decrease in prevalence in Zambia. We therefore aimed to examine the putative association between decreasing LF prevalence and increasing coverage of insecticide-treated mosquito nets (ITNs) for malaria vector control, by comparing LF mapping data collected between 2003-2005 and 2009-2011 to LF sentinel site prevalence data collected between 2012 and 2014, before any anti-LF MDA was started. The coverage of ITNs for malaria was quantified and compared for each site in relation to the dynamics of LF. We found a significant decrease in LF prevalence from the years 2003-2005 (11.5% CI95 6.6; 16.4) to 2012-2014 (0.6% CI95 0.03; 1.1); at the same time, there was a significant scale-up of ITNs across the country from 0.2% (CI95 0.0; 0.3) to 76.1% (CI95 71.4; 80.7) respectively. The creation and comparison of two linear models demonstrated that the geographical and temporal variation in ITN coverage was a better predictor of LF prevalence than year alone. Whilst a causal relationship between LF prevalence and ITN coverage cannot be proved, we propose that the scale-up of ITNs has helped to control Anopheles mosquito populations, which have in turn impacted on LF transmission significantly before the scale-up of MDA. This putative synergy with vector control has helped to put Zambia on track to meet national and global goals of LF elimination by 2020.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Parasite Epidemiology and Control - Volume 2, Issue 4, November 2017, Pages 7-14
Journal: Parasite Epidemiology and Control - Volume 2, Issue 4, November 2017, Pages 7-14
نویسندگان
M. Nsakashalo-Senkwe, E. Mwase, E. Chizema-Kawesha, V. Mukonka, P. Songolo, F. Masaninga, M.P. Rebollo, B. Thomas, M.J. Bockarie, H. Betts, J.R. Stothard, L.A. Kelly-Hope,