Effect of Convection on Polymerase Chain Reaction in a Closed Cell

The effect of natural convection on polymerase chain reaction (PCR), where many copies of a DNA template are made by cycling between hot and cold regions is investigated. A model of a Rayleigh-Benard in squared closed cell is employed by the problem. Heat and mass transfer of reagents and DNA concentrations evolution are described by the system of equations in the Boussinesq approximation [1] and by the convection-diffusion-reaction equations respectively.