The effects of pulse‐delivered inhaled nitric oxide on arterial oxygenation, ventilation‐perfusion distribution and plasma endothelin‐1 concentration in laterally recumbent isoflurane‐anaesthetized horses

PiNO delivered in the initial portion of the inspiration effectively relieves hypoxaemia in anaesthetized horses by improving V˙A/ Q˙ matching and decreasing Q˙S/ Q˙t without affecting ET‐1.