Application of the Forgotten Effects Model to the Economic Effects for Public European Health Systems by the Early Diagnostics of Emergent and Rare Diseases

The development of new, evidence-based treatments relies on an improved understanding of the often very complex pathophysiology of diseases. The systems (bio) medicine approaches have the potential to tackle this complexity through the integration of a variety of biological and medical research data and computational modelling. A European collaborative approach is required to assemble the necessary multidisciplinary expertise (e.g. biology, medicine, mathematics, computational technologies, and economics) to implement these last systems, which are approached in order to reduce the cost of the European Public Health System and simultaneously improve the wellbeing among citizens.