The determination of the hydrodynamic diameter of magnetic particles using FRS experiment

A new method for the determination of the size distribution of magnetic carrier systems, as well as for the proof of successful immobilization of biomolecules to magnetic particles was developed and tested. The method is based on the Forced Rayleigh Scattering (FRS) experiment, in which a diffraction concentration grating is created in a thin sample of colloidal fluid due to the absorption of an optical interference field.