کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
9867678 | 1530098 | 2005 | 7 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Conversion of a proton pair para order into 13C polarization by rf irradiation, for use in MRI
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کلمات کلیدی
موضوعات مرتبط
مهندسی و علوم پایه
فیزیک و نجوم
فیزیک و نجوم (عمومی)
پیش نمایش صفحه اول مقاله
![عکس صفحه اول مقاله: Conversion of a proton pair para order into 13C polarization by rf irradiation, for use in MRI Conversion of a proton pair para order into 13C polarization by rf irradiation, for use in MRI](/preview/png/9867678.png)
چکیده انگلیسی
We describe the theory of production of hyperpolarized 13C in small organic molecules, for use as molecular contrast agents in MRI, by a two-step process. The first is a catalyzed hydrogenation with para-hydrogen in a small dc magnetic field under rf irradiation, resulting in a molecular proton pair in the pure para state. The second step converts this para order into net hyperpolarization of a nearby carbon 13 through a sequence of rf pulses at the resonance frequencies of both spin species. The final theoretical polarization is close to unity. The whole process, which was successfully implemented, takes a few seconds. To cite this article: M. Goldman, H. Jóhannesson, C. R. Physique 6 (2005).
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Comptes Rendus Physique - Volume 6, Issues 4â5, MayâJune 2005, Pages 575-581
Journal: Comptes Rendus Physique - Volume 6, Issues 4â5, MayâJune 2005, Pages 575-581
نویسندگان
Maurice Goldman, Haukur Jóhannesson,