کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
9877614 1534086 2005 10 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Implications of long tails in the distribution of mutant effects
کلمات کلیدی
موضوعات مرتبط
مهندسی و علوم پایه ریاضیات ریاضیات کاربردی
پیش نمایش صفحه اول مقاله
Implications of long tails in the distribution of mutant effects
چکیده انگلیسی
Long-tailed distributions possess an infinite variance, yet a finite sample that is drawn from such a distribution has a finite variance. In this work we consider a model of a population subject to mutation, selection and drift. We investigate the implications of a long-tailed distribution of mutant allelic effects on the distribution of genotypic effects in a model with a continuum of allelic effects. While the analysis is confined to asexual populations, it does also have implications for sexual populations. We obtain analytical results for a selectively neutral population as well as one subject to selection. We supplement these analytical results with numerical simulations, to take into account genetic drift. We find that a long-tailed distribution of mutant effects may affect both the equilibrium and the evolutionary adaptive behaviour of a population.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Physica D: Nonlinear Phenomena - Volume 206, Issues 3–4, 1 July 2005, Pages 265-274
نویسندگان
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