کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
9910153 | 1548652 | 2005 | 14 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Microsatellite mutations show no increases in the children of the Chernobyl liquidators
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موضوعات مرتبط
علوم زیستی و بیوفناوری
بیوشیمی، ژنتیک و زیست شناسی مولکولی
تحقیقات سرطان
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چکیده انگلیسی
At the Y-linked loci, the mutation rates (expressed as number of mutations among the total number of loci for the individuals included) are 2.9Â ÃÂ 10â3 (4/1392) and 2.1Â ÃÂ 10â3 (3/1458) in the children of exposed and control parents, respectively. This difference is not statistically significant. At the autosomal loci, the corresponding estimates are 5.9Â ÃÂ 10â3 (11/1862; exposed group) and 8.5Â ÃÂ 10â3 (18/2108; control). Again, the difference is not significant. The possibility that the Belarusian population might have been unexpectedly exposed to some chemical contaminants in the environment appears unlikely in view of the finding that the spontaneous mutation rates at the same set of loci in several non-Belarusian populations were similar to those in Belarus. The estimated mean radiation dose to the liquidators was small, being about 39Â mSv, and this might be one reason why no increases in mutation rates due to radiation could be found.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Mutation Research/Genetic Toxicology and Environmental Mutagenesis - Volume 581, Issues 1â2, 7 March 2005, Pages 69-82
Journal: Mutation Research/Genetic Toxicology and Environmental Mutagenesis - Volume 581, Issues 1â2, 7 March 2005, Pages 69-82
نویسندگان
Katsumi Furitsu, Haruko Ryo, Klaudiya G. Yeliseeva, Le Thi Thanh Thuy, Hiroaki Kawabata, Evelina V. Krupnova, Valentina D. Trusova, Valery A. Rzheutsky, Hiroo Nakajima, Nikolai Kartel, Taisei Nomura,