دانلود مقالات ISI درباره Γh2Ax + ترجمه فارسی

Increased expression of phosphorylated NBS1, a key molecule of the DNA damage response machinery, is an adverse prognostic factor in patients with de novo myelodysplastic syndromes

Keywords: Myelodysplastic syndromes; DNA damage response; pNBS1; pATM; γH2AX;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2013 سفارش ترجمه

SYCP3-like X-linked 2 is expressed in meiotic germ cells and interacts with synaptonemal complex central element protein 2 and histone acetyltransferase TIP60

Keywords: SYCP3; synaptonemal complex protein 3; SLX2; SYCP3-like X-linked 2; SYCE2; synaptonemal complex central element protein 2; TIP60; histone acetyltransferase Tip60; γH2AX; phosphorylated histone H2AX; Xlr; X-linked lymphocyte regulated; Xmr; Xlr-related me

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2013 سفارش ترجمه

Assessment of the in vitro γH2AX assay by High Content Screening as a novel genotoxicity test

Keywords: γH2AX; Genotoxicity; In vitro; DNA damage; Double strand breaks;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2013 سفارش ترجمه

Role of TRPM2 and TRPV1 cation channels in cellular responses to radiation-induced DNA damage

Keywords: ADPR; adenine 5′-diphosphoribose; 2-APB; 2-aminoethoxydiphenyl borate; ATM; ataxia telangiectasia mutated; 53BP1; tumor suppressor p53-binding protein 1; CAP; capsaicin; CPZ; capsazepine; DPQ; 3,4-dihydro-5-[4-(1-piperidinyl)butoxy]-1(2H)-isoquinolinone

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2013 سفارش ترجمه

Studying the cerebellar DNA damage response in the tissue culture dish

Keywords: 53BP1; p53 binding protein 1; AOA1/2; ataxia with oculomotor apraxia type 1; A-T; ataxia-telangiectasia; A-TLD; ataxia-telangiectasia-like disorder/disease; ATM; ataxia-telangiectasia, mutated; ATR; ATM- and Rad3-related protein kinase; CaBP; calbindin pr

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2013 سفارش ترجمه

Melatonin ameliorates bisphenol A-induced DNA damage in the germ cells of adult male rats

Keywords: Bisphenol A; Melatonin; Germ cells; DNA damage; γH2AX; Oxidative stress;

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2013 سفارش ترجمه

Effects of 100 MeV protons delivered at 0.5 or 1 cGy/min on the in vivo induction of early and delayed chromosomal damage

Keywords: Protons; mFISH; γH2AX; Bone marrow; Mice; Genomic instability;

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2013 سفارش ترجمه

Coilin levels modulate cell cycle progression and γH2AX levels in etoposide treated U2OS cells

Keywords: Coilin; DNA damage; Cell cycle; γH2AX;

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2012 سفارش ترجمه

Trypanosomal histone γH2A and the DNA damage response

Keywords: Checkpoint; Chromatin; γH2AX; I-SceI; MMS; Repair;

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2012 سفارش ترجمه

Dynamics of γH2AX formation and elimination in mammalian cells after X-irradiation

Keywords: Ionizing radiation; Histone H2AX phosphorylation; DNA double-strand breaks; Bystander effect; Non-proliferating mammalian tissues; γH2AX; histone H2AX with phosphorylated C-terminal serine; DSB; double-strand DNA break; IR; X-irradiation;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2012 سفارش ترجمه

Renal and glycemic effects of high-dose chromium picolinate in db/db mice: assessment of DNA damage

Keywords: Diabetes; Chromium picolinate; Kidney; Albuminuria; 8-OHdG; γH2AX;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2012 سفارش ترجمه

Disruptive cell cycle regulation involving epigenetic downregulation of Cdkn2a (p16Ink4a) in early-stage liver tumor-promotion facilitating liver cell regeneration in rats

Keywords: BNF; β-naphthoflavone; Cdc2; cell division cycle 2; Cdc25c; cell division cycle 25 homolog C (S. pombe); Cdk; cyclin-dependent kinase; Chk1; checkpoint kinase 1; CKI; cyclin-dependent kinase inhibitor; DEN; N-diethylnitrosamine; FB; fenbendazole; γH2AX;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2012 سفارش ترجمه

γH2AX as a novel endpoint to detect DNA damage: Applications for the assessment of the in vitro genotoxicity of cigarette smoke

Keywords: γH2AX; DNA; DNA damage; In vitro; Genotoxicity; Cigarette smoke;

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2012 سفارش ترجمه

Residual DNA and chromosomal damage in ex vivo irradiated blood lymphocytes correlated with late normal tissue response to breast radiotherapy

Keywords: DNA double-strand break; γH2AX; Chromosomal aberration; Blood lymphocyte radiosensitivity; Late normal tissue damage;

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2011 سفارش ترجمه

Retention of γH2AX foci as an indication of lethal DNA damage

Keywords: γH2AX; DNA damage; Prediction; Tumour response;

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2011 سفارش ترجمه

Repeated exposure of human fibroblasts to ionizing radiation reveals an adaptive response that is not mediated by interleukin-6 or TGF-β

Keywords: Adaptive response; Cytokines; DNA repair response; γH2AX; Non-targeted effects;

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2011 سفارش ترجمه

Structural basis of γH2AX recognition by human PTIP BRCT5-BRCT6 domains in the DNA damage response pathway

Keywords: PTIP; Pax2 transactivation domain interaction protein; BRCT; BRCA1 C-terminal domain; DDR; DNA damage response; IR; ionizing radiation; FPA; fluorescence polarization assays; IRIF; ionizing radiation-induced focus; RMSD; root mean-square deviation; PA1; P

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2011 سفارش ترجمه

Ectopic expression of H2AX protein promotes TrkA-induced cell death via modulation of TrkA tyrosine-490 phosphorylation and JNK activity upon DNA damage

Keywords: TrkA; γH2AX; DNA damage; Cell death; JNK;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2011 سفارش ترجمه

ALCAPs induce mitochondrial apoptosis and activate DNA damage response by generating ROS and inhibiting topoisomerase I enzyme activity in K562 leukemia cell line

Keywords: γH2AX; modified and phosphorylated histone 2A; ATM; ataexia telangiectasia mutated; PARP; poly-ADP ribose polymerase; CHK2; checkpoint kinase 2; CPT-11; irinotecan; Doxo; doxorubicin; l-NAC; l-N-acetyl-cysteine; ROS; Topoisomerase I inhibition; γH2AX; A

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2011 سفارش ترجمه

Residual DNA double strand breaks in perfused but not in unperfused areas determine different radiosensitivity of tumours

Keywords: γH2AX; Radiotherapy; DNA repair; Hypoxia; Local tumour control; Perfusion;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2011 سفارش ترجمه

Inhibition of REV3 Expression Induces Persistent DNA Damage and Growth Arrest in Cancer Cells

Keywords: TLS; DNA translesion synthesis; Pol ζ; DNA translesion synthesis polymerase ζ; REV3; the mammalian REV3L gene; MEF; mouse embryonic fibroblast; DDR; DNA damage response; DSBs; DNA double-strand breaks; ATM; ataxia-telangiectasia mutated; γH2AX; phospho

دانلود رایگان متن کامل مقاله ISI 15 صفحه سال انتشار : 2011 سفارش ترجمه

Extensive glial apoptosis develops early after hypoxic-dysmetabolic insult to the neonatal rat spinal cord in vitro

Keywords: astrocyte; oligodendrocyte; locomotion; ischemia; spinal injury; CV; coefficient of period variation; DAPI; 4′,6-diamidino-2-phenylindole; DSB; double-stranded breaks; GFAP; glial fibrillary acidic protein; γH2AX; phosphorylated (Ser 139) histon H2A.X;

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2010 سفارش ترجمه

Differences in heating methods may account for variation in reported effects on γH2AX focus formation

Keywords: Heat shock; DNA damage; γH2AX; Cytotoxicity;

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2009 سفارش ترجمه

Induction and Rejoining of DNA Double Strand Breaks Assessed by H2AX Phosphorylation in Melanoma Cells Irradiated with Proton and Lithium Beams

Keywords: Ionizing radiation; LET; DNA DSB; Melanoma cells; γH2AX;

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2009 سفارش ترجمه

Differences in DNA damage and repair produced by systemic, hepatocarcinogenic and sarcomagenic dibenzocarbazole derivatives in a model of rat liver progenitor cells

Keywords: AFB1; aflatoxin B1; B[a]P; benzo[a]pyrene; DBC; 7H-dibenzo[c,g]carbazole; DiMeDBC; 5,9-dimethyldibenzo[c,g]carbazole; Fpg; formamidopyrimidine-DNA glycosylase/AP endonuclease; γH2AX; histone H2AX phosphorylated on Ser139; MI; mitotic index; MNi; micronuc

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2009 سفارش ترجمه

Bystander Effects Induced by Continuous Low-Dose-Rate 125I Seeds Potentiate the Killing Action of Irradiation on Human Lung Cancer Cells In Vitro

Keywords: 125I seed; Bystander effect; γH2AX; Micronucleus; Human lung cancer cells;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2008 سفارش ترجمه

DNA Double-Strand Break Rejoining in Complex Normal Tissues

Keywords: DNA double-strand breaks; DSB rejoining; DNA repair; γH2AX; Normal tissue; Radiosensitivity;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2008 سفارش ترجمه

In Vivo Bystander Effect: Cranial X-Irradiation Leads to Elevated DNA Damage, Altered Cellular Proliferation and Apoptosis, and Increased p53 Levels in Shielded Spleen

Keywords: Bystander effect; Mouse model; Apoptosis; Proliferation; DNA damage; γH2AX; p53;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2008 سفارش ترجمه

X-irradiation of cells on glass slides has a dose doubling impact

Keywords: γH2AX; DSBs; Immunofluorescence;

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2007 سفارش ترجمه

Growth stimulation of UV-induced DNA damage retaining epidermal basal cells gives rise to clusters of p53 overexpressing cells

Keywords: UV; ultraviolet; UVB; ultraviolet B; BCC; basal cell carcinoma; SCC; squamous cell carcinoma; MED; minimal erythema dose; CPDs; cyclobutane pyrimidine dimers; (6-4)PPs; pyrimidine (6-4) pyrimidone photoproducts; CRBCs; CPD-retaining basal cells; UV-DDB; U

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2007 سفارش ترجمه

Nitric Oxide and Acid Induce Double-Strand DNA Breaks in Barrett's Esophagus Carcinogenesis via Distinct Mechanisms

Keywords: AA; ascorbic acid; BE; Barrett's esophagus; CCCP; carbonyl cyanide m-chlorophenylhydrazone; CM-H2DCFDA; 5-(and-6)-chloromethyl-2′,7′-dichlorodihydrofluorescein diacetate, acetyl ester; DAF-FM; 4-amino-5-methylamino-2′,7′-difluorofluorescein; DSB

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2007 سفارش ترجمه

Collaborative roles of γH2AX and the Rad51 paralog Xrcc3 in homologous recombinational repair

Keywords: γH2AX; Rad51 paralog; Homologous recombination; Genome stability; Double-strand break repair;

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2007 سفارش ترجمه

Does γH2AX foci formation depend on the presence of DNA double strand breaks?

Keywords: γH2AX; Double strand break; Replication arrest; Environmental factors;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2005 سفارش ترجمه

DNA-PK is responsible for enhanced phosphorylation of histone H2AX under hypertonic conditions

Keywords: γH2AX; ATM; DNA-PK; Double-strand breaks; Comet assay;

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2005 سفارش ترجمه