Phosphatidylinositol-3,4,5-trisphosphate stimulates Ca2Â + elevation and Akt phosphorylation to constitute a major mechanism of thromboxane A2 formation in human platelets
Keywords: (DiC16-PIP3); 1-O-(1,2-di-palmitoyl-sn-glyero-3-O-phosphoryl)-D-myo-inositol-3,4,5-trisphosphate; (DiC8-PIP3); 1-O-(1,2-di-octanoyl-sn-glyero-3-O-phosphoryl)-D-myo-inositol-3,4,5-trisphosphate; (SOCE); store operated Ca2Â + entry; (PLC); phospholipase C;