دانلود مقالات ISI درباره 17,20-Lyase + ترجمه فارسی

ReviewStructural insights into the function of steroidogenic cytochrome P450 17A1

Keywords: Steroidogenesis; Cytochrome P450 17A1; X-ray crystallography; 17α−hydroxylase; 17,20-Lyase;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2017 سفارش ترجمه

The diverse chemistry of cytochrome P450 17A1 (P450c17, CYP17A1)

Keywords: Androgen; 17-Hydroxylase; 17,20-Lyase; Hypertension; Metabolic switching; Steroidogenesis; Cytochrome P450

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2015 سفارش ترجمه

Effect of an investigational CYP17A1 inhibitor, orteronel (TAK-700), on estrogen- and corticoid-synthesis pathways in hypophysectomized female rats and on the serum estradiol levels in female cynomolgus monkeys

Keywords: Orteronel; 17,20-Lyase; Estradiol; Progesterone; Rat; Cynomolgus monkey;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2013 سفارش ترجمه

The activities of 5α-reductase and 17,20-lyase determine the direction through androgen synthesis pathways in patients with 21-hydroxylase deficiency

Keywords: Backdoor pathway; 21-Hydroxylase deficiency; 17α-Hydroxyallopregnanolone; 5α-Pregnane-3α; 17α-Diol-20-one; 5α-Reductase; 17,20-Lyase;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2012 سفارش ترجمه

The Role of Abiraterone Acetate in the Management of Prostate Cancer: A Critical Analysis of the Literature

Keywords: Abiraterone acetate (AA); Castration resistant prostate cancer (CRPC); Secondary hormonal therapy; CYP17; 17 α-Hydroxylase; 17,20-Lyase

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2011 سفارش ترجمه

17,20-Lyase inhibitors. Part 3: Design, synthesis, and structure–activity relationships of biphenylylmethylimidazole derivatives as novel 17,20-lyase inhibitors

Keywords: 17,20-Lyase; Testosterone; DHEA; Prostate cancer

دانلود رایگان متن کامل مقاله ISI 15 صفحه سال انتشار : 2011 سفارش ترجمه

Discovery of orteronel (TAK-700), a naphthylmethylimidazole derivative, as a highly selective 17,20-lyase inhibitor with potential utility in the treatment of prostate cancer

Keywords: CRPC; castration-resistant prostate cancer; CYP; cytochrome P450; DHEA; dehydroepiandrosterone; LH-RH; luteinizing-hormone-releasing-hormone; TAK-700; 17,20-Lyase; Prostate cancer; Orteronel;

دانلود رایگان متن کامل مقاله ISI 17 صفحه سال انتشار : 2011 سفارش ترجمه

17,20-Lyase inhibitors. Part 4: Design, synthesis and structure-activity relationships of naphthylmethylimidazole derivatives as novel 17,20-lyase inhibitors

Keywords: 17,20-Lyase; 11-Hydroxylase; Testosterone; Prostate cancer;

دانلود رایگان متن کامل مقاله ISI 20 صفحه سال انتشار : 2011 سفارش ترجمه

Synthesis and biochemical evaluation of a range of (4-substituted phenyl)sulfonate derivatives of 4-hydroxybenzyl imidazole-based compounds as potent inhibitors of 17α-hydroxylase/17,20-lyase (P45017α) derived from rat testicular microsomes

Keywords: Synthesis; Inhibition; Enzyme; 17α-Hydroxylase; 17,20-Lyase;

دانلود رایگان متن کامل مقاله ISI 4 صفحه سال انتشار : 2010 سفارش ترجمه

Steroid biosynthetic enzyme activities in leachate-exposed female perch (Perca fluviatilis) as biomarkers for endocrine disruption

Keywords: Reproductive failure; Aromatase; 17,20-lyase; 17α-hydroxylase; 17β-hydroxysteroid dehydrogenase; Refuse dump leachate

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2006 سفارش ترجمه

Treatment with high-dose estrogen (diethylstilbestrol) significantly decreases plasma estrogen and androgen levels but does not influence in vivo aromatization in postmenopausal breast cancer patients

Keywords: Breast cancer; Aromatase; Diethylstilbestrol; Estrogens; Androgens; 17,20-Lyase;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2005 سفارش ترجمه